Garcinia cambogia reportedly does not have any known adverse effects in healthy adults, but there are some people who are advised not to take it. According to experts, this includes children, pregnant and lactating women, those diagnosed with diabetes mellitus, and people with Alzheimers or other forms of dementia disease. In the case of Alzheimers patients, it is thought HCA might form acetylcholine in the brain, while diabetics could be affected by HCAs tendency to lower blood sugar. Conversely, in healthy adults this latter effect can purportedly curb cravings for sweets and carbohydrates.

Garcinia cambogia is usually sold in capsule form, standardized to include a percentage of HCA, the active ingredient. Only brands standardized to 50% or greater HCA are generally recommended. For maximum effect, the daily dose is divided in three parts, taking one or more capsules 30-60 minutes before breakfast, lunch, and dinner.

Some manufacturers claim garcinia cambogia must build up in the system before the full benefits can be realized. It has also been suggested that HCA might help people who have already attained their ideal weight to maintain it. The Food and Drug Administration (FDA) does not regulate garcinia cambogia. People who are considering augmenting a healthy diet and exercise regimen with herbal aids like HCA should see their physicians for personalized advice.

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